1 Data on File- As of 6.22.2020 of marketed pen needles in the USA, Canada.
2 De Berardis G, Scardapane M, Lucisano G, et al. Efficacy, safety and acceptability of the new pen needle 34Gx3.5mm: a crossover randomized non-inferiority trial; AGO 02 study. CMRO. 2018; 34(9): 1699-1704.
3Leonardi L, Vigano M, Nicolucci A. Penetration force and cannula sliding profiles of different pen needles: the PICASSO study. Medical Devices: Evidence and Research. 2019; 12: 311-317.
4Egekvist H, Bjerring P, Arendt-Nielsen L. Pain and mechanical injury of human skin following needle insertions. Eur J Pain. 1999; 3: 41-49.
5 Arendt-Nielsen L, Egekvist H, Bjerring P. Pain following controlled cutaneous insertion of needles with different diameters. Somatosensory and Motor Research. 2006; 23(1/2): 37-43.
6Praestmark KA, Jensen ML, Madsen NB, et al. Pen needle design influences ease of insertion, pain, and skin trauma in subjects with type 2 diabetes. BMJ Open Diabetes Research and Care. 2016; 4: e000266.
7Data on File- Technical Data Sheet.
8Data on File- Fact-Finding Questionnaire For Satisfaction Rating Among Diabetic Patients Of Insupen Pen Needle With New Sharpening. 47 participants injecting up to 4 times daily over a 2 week period.
9Data on File- Focus Group Feedback August 2019.
10Frid AH, Kreugel G, Grassi G, et al. New Insulin Delivery Recommendations. Mayo Clin Proc. 2016; 91(9): 1231-1255.